Fig. 2From: Whole-genome sequencing of glioblastoma reveals enrichment of non-coding constraint mutations in known and novel genesGERP score distribution for the SweGBM-1 cohort. a Scores range from − 12 to + 7; approximately 15% of all variants, with GERP RS ≥ 2 are deemed to be “constrained” (marked in red). b Distribution of variants in constrained sites by category for coding and non-coding mutations (see the inset for the mutation type color code)Back to article page