Fig. 5

Developmental delay and accelerated maternal RNA clearance induced by Elavl1a deficiency. a Elavl1a deficiency leads to developmental delay during zebrafish early embryogenesis. b Zebrafish elavl1a mRNA with MO-mismatch binding site can partially rescue the phenotype in elavl1a morphants. c Cumulative distribution of the log₂ fold changes of RNA level between control and elavl1a morphants during the period of 4 h.p.f. to 6 h.p.f.. P values were calculated by two-sided Kolmogorov-Smirnov test. d Cumulative distribution of the log₂ fold changes of RNA level of elavl1a morphants versus control in maternal decay, maternal stable and zygotic groups at 6 h.p.f.. P values were calculated by two-sided Kolmogorov-Smirnov test. e Gene set enrichment analysis of downregulated genes upon Elavl1a deficiency