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Fig. 2 | Genome Biology

Fig. 2

From: Characterisation of genetic regulatory effects for osteoporosis risk variants in human osteoclasts

Fig. 2

Analysis of the eBMD GWAS and osteoclast eQTL datasets using the GARFIELD software [24] demonstrated significant enrichment of osteoporosis risk variants among osteoclast eQTL across four GWAS P value thresholds (P < 1 × 10−5, 1 × 10−6, 1 × 10−7 and 1 × 10−8), with the enrichment results for the trait neuroticism [25] included for comparison. The upper panels present the −log10 enrichment P values for each threshold, while the lower panels present the natural logarithm of the odds ratios for each threshold with 95% confidence intervals

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