Fig. 4

PWMs grouping according to the similarity of their performance measure values across data sets. PWMs recognizing bound regions in similar selections of experiments are grouped reasonably well according to their TFClass families. Dimensionality reduction with t-SNE is applied to motifs’ performance at ChIP-seq (a), HT-SELEX 10% (b), and PBM data (c). For illustration, several TF families are highlighted with color. Each point corresponds to a PWM. Source coordinates are AUC ROC values (a, b) or Pearson correlation coefficients (c) calculated for different data sets. ‘o’ HOCOMOCO and JASPAR PWMs, ‘x’ CIS-BP PWMs