Fig. 1
From: CRISPRi-based radiation modifier screen identifies long non-coding RNA therapeutic targets in glioma
A glioma cell culture model for identifying radiation sensitizers. a Doubling time of U87 GBM cells in culture after treatment with different amounts of single-dose or fractionated radiation. Fractionated (fx) radiation (8 Gy in 4 fx) was delivered in 2 Gy doses every other day (n = 3 biological replicates per condition; error bar = SD). b, c Internally controlled growth assays for U87 cells evaluating CRISPRi knockdown of ERCC6L2 with (b) and without (c) radiation (n = 3 biological replicates per condition; error bar = SD; two-tailed Student’s t test of end points; radiation delivery timepoints indicated below the x-axis)