TY - JOUR AU - Avelar, Roberto A. AU - Ortega, Javier Gómez AU - Tacutu, Robi AU - Tyler, Eleanor J. AU - Bennett, Dominic AU - Binetti, Paolo AU - Budovsky, Arie AU - Chatsirisupachai, Kasit AU - Johnson, Emily AU - Murray, Alex AU - Shields, Samuel AU - Tejada-Martinez, Daniela AU - Thornton, Daniel AU - Fraifeld, Vadim E. AU - Bishop, Cleo L. AU - de Magalhães, João Pedro PY - 2020 DA - 2020/04/07 TI - A multidimensional systems biology analysis of cellular senescence in aging and disease JO - Genome Biology SP - 91 VL - 21 IS - 1 AB - Cellular senescence, a permanent state of replicative arrest in otherwise proliferating cells, is a hallmark of aging and has been linked to aging-related diseases. Many genes play a role in cellular senescence, yet a comprehensive understanding of its pathways is still lacking. SN - 1474-760X UR - https://doi.org/10.1186/s13059-020-01990-9 DO - 10.1186/s13059-020-01990-9 ID - Avelar2020 ER -