Fig. 5
From: HiNT: a computational method for detecting copy number variations and translocations from Hi-C data
Comparison of breakpoints detected from Hi-C and WGS. a Overlap of the translocation breakpoints detected by Meerkat (WGS), Delly (WGS), and HiNT (Hi-C). b The Hi-C interaction map containing a breakpoint detected in both Hi-C and WGS. c The same exact breakpoint in panel B is captured in WGS. Discordant reads in light green (dark green) are paired end reads whose mates are found on chr9 (chr22). d Hi-C interaction map illustrating a clear case of a translocation detected only by HiNT. e Breakpoints detected in both Meerkat and Delly (“WGS Common”) and only in Hi-C only are classified into small repeat, large repeat, and non-repeat regions, showing that Hi-C is enriched for SVs involving large repeats