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Fig. 5 | Genome Biology

Fig. 5

From: High-resolution Repli-Seq defines the temporal choreography of initiation, elongation and termination of replication in mammalian cells

Fig. 5

Developmentally controlled IZs show minimal RT switches and occasional transcriptional changes. a mESC and mNPC Log2E/L RT centred at ESC unique IZs (left panel) and NPC unique IZs (right panel) ± 1 MB. Line plots were colour-coded with blue and red representing negative and positive log2E/L RT. b Distributions of expression differences of genes overlapping with ESC and NPC unique IZs (calculated as log2(mESC RPKM/mNPC RPKM)). Expression differences were colour-coded by false discovery rate (FDR) from 0 to 1. c Scatter plots showing that the expression differences were colour-coded by FDR from 0 to 1

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