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Fig. 4 | Genome Biology

Fig. 4

From: High-resolution Repli-Seq defines the temporal choreography of initiation, elongation and termination of replication in mammalian cells

Fig. 4

Correlation between IZs and histone modifications is cell type and timing specific. a–d Mean line plots (top row) and heatmaps (bottom row) of H3K27ac, H3K4me3, H3K9me3 and H3K27me3 fold enrichment signal centred on early (red), early-mid (blue), late-mid (green) and late (black) IZs ± 500 kb in H9 (a), HCT116 (b), mESC (c) and mNPC (d). e Mean line plots (top row) and heatmaps (bottom row) of H3K27ac, H3K4me3, H3K9me3 and H3K27me3 fold enrichment signal centred on TTRs ± 500 kb in H9, HCT116, mESC and mNPC. Green and orange lines/heatmaps indicate rightward and leftward TTRs, respectively

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Genome Biology

ISSN: 1474-760X

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