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Fig. 3 | Genome Biology

Fig. 3

From: DENDRO: genetic heterogeneity profiling and subclone detection by single-cell RNA sequencing

Fig. 3

Clonal composition alternations with anti-PD1 treatments and cell lines. a Experimental overview. For each condition at day 15, we have two biological replicates. There are total 600 cells from 6 tumors sequenced. b DENDRO cluster result. No clone is exclusively associated with any tumor condition. c Frequencies of the subclonal populations in B16, B16PD1, and R499. d Neighbor-joining phylogenetic tree given detected subclones. e Number of high-affinity neoantigens predicted for each clone. Clone 2 has the highest number of neoantigens

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