Fig. 3
From: HIFI: estimating DNA-DNA interaction frequency from Hi-C data at restriction-fragment resolution
HIFI-MRF reveals fine-scale regulatory contacts in Hi-C data. Heatmap (a) and virtual 4C [60, 61] plots based on raw, binned, or HIFI-MRF processed data (b) showing the long-range interaction between Tsix and its transcriptional regulator, Linx, on chromosome X of female mice as observed by Nora et al. [7] using 5C. This interaction is more easily observed in HIFI-MRF data than in raw or binned Hi-C data