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Fig. 6 | Genome Biology

Fig. 6

From: CHROMATIX: computing the functional landscape of many-body chromatin interactions in transcriptionally active loci from deconvolved single cells

Fig. 6

Functional landscape of 3-body chromatin interactions. Pie (a, c) and corresponding sunburst (b, d) charts for the proportion of specific (bottom) and non-specific (top) 3-body interactions involving the functional genomic regions of super-enhancer (SE), enhancer (E), and promoter (P). The innermost ring of the sunburst charts (b, d) are the same as the corresponding pie charts of (a, c), with outer rings representing the sub-fractions of interacting partners with SE, E, or P functional associations. Gaps in the sunburst charts represent the fractions of interacting partners with no known SE, E, or P annotation. Here, 3-body interactions are not required to be maximal and can be part of a larger many-body complex where all regions are within 80 nm. Plots shown are the averages across all 39 modeled genomic loci

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