Fig. 2

CHROMATIX Hi-C reconstruction. Four representative genomic regions (a–d), with the measured Hi-C [9] on the upper triangle and the simulated Hi-C from aggregation of 3-D polymer folds on the lower triangle. The Pearson correlations between simulated and measured Hi-C for all 39 modeled genomic loci have approximate mean of 0.96±0.003 SEM, after removal of the first 2 diagonals. DNase data are from ENCODE [53, 54] (ENCSR000EMT) with corresponding signal, gene, and chromosome diagrams from UCSC genome browser [76, 77]. All heatmaps are in units of 5 KB