Table 1 Independent breast cancer risk signals with ≤ 2 candidate protein-coding genes
From: Chromatin interactome mapping at 139 independent breast cancer risk signals
Cytoband | Locus | Signal | Target gene/s | Cytoband | Locus | Signal | Target gene/s |
|---|---|---|---|---|---|---|---|
1p22.3 | chr1:87656923_88656923 | 2 | LMO4 | 8q24.21 | chr8:127424659_130041931 | 3 | MYC |
1q32.1 | chr1:200937832_201937832 | 1 | IPO9 | 9q31.2 | chr9:109803808_111395353 | 1 | KLF4 |
2p23.3 | chr2:28670676_29670676 | 1 | ALK,SPDYA | 9q33.1 | chr9:118813486_119813486 | 1 | PAPPA |
2p24.1 | chr2:18815791_19820803 | 1 | OSR1 | 10p14 | chr10:8588113_9588113 | 1 | GATA3 |
2q35 | chr2:217405832_218796508 | 1 | IGFBP5 | 10q25.2 | chr10:114273927_115286154 | 1 | TCF7L2 |
2q35 | chr2:217405832_218796508 | 3 | IGFBP5 | 10q26.12 | chr10:122593901_123849324 | 2 | FGFR2 |
3p24.1 | chr3:26827965_28285247 | 2 | AZI2,CMC1 | 11p15.5 | chr11:1398664_2442575 | 1 | LSP1 |
3q23 | chr3:140612859_141612859 | 1 | ZBTB38 | 11q13.3 | chr11:68831418_69879161 | 1 | MYEOV |
4p14 | chr4:38312876_39312876 | 1 | TBC1D1,TLR10 | 11q13.3 | chr11:68831418_69879161 | 2 | MYEOV |
4q24 | chr4:105569013_106856761 | 1 | GSTCD,PPA2 | 11q13.3 | chr11:68831418_69879161 | 3 | MYEOV |
5p13.3 | chr5:32067732_33067732 | 1 | ZFR | 11q24.3 | chr11:128952507_129961171 | 1 | BARX2 |
5p15.33 | chr5:779790_1797488 | 1 | SLC6A18 | 12p11.22 | chr12:27639846_29034415 | 1 | CCDC91 |
5p15.33 | chr5:779790_1797488 | 2 | SLC6A18 | 12p13.1 | chr12:13913931_14913931 | 1 | ATF7IP |
5q11.1 | chr5:49141645_50695093 | 2 | CTD-2203A3.1,ISL1 | 12q22 | chr12:95527759_96527759 | 1 | NTN4,RP11-536G4.1 |
5q11.2 | chr5:55531884_56587883 | 1 | MAP3K1 | 12q24.21 | chr12:115336522_116336522 | 1 | TBX3 |
5q11.2 | chr5:55531884_56587883 | 4 | MAP3K1 | 12q24.21 | chr12:115336522_116336522 | 2 | TBX3 |
5q11.2 | chr5:55531884_56587883 | 5 | MAP3K1 | 12q24.21 | chr12:115336522_116336522 | 3 | TBX3 |
5q11.2 | chr5:57684061_58865569 | 1 | GAPT | 13q13.1 | chr13:32468810_33472626 | 1 | FRY |
5q11.2 | chr5:57684061_58865569 | 2 | PDE4D | 13q22.1 | chr13:73464519_74464519 | 1 | KLF5 |
5q33.3 | chr5:157730013_158744083 | 1 | EBF1 | 14q13.3 | chr14:36632769_37635752 | 1 | SLC25A21,SLC25A21-AS1 |
6p22.3 | chr6:15899557_16899557 | 1 | ATXN1 | 14q24.1 | chr14:68117194_69534682 | 1 | ZFP36L1 |
6q14.1 | chr6:81628386_82795951 | 1 | AL359693.1 | 14q24.1 | chr14:68117194_69534682 | 2 | ZFP36L1 |
6q23.1 | chr6:129849119_130849119 | 1 | AKAP7,TMEM244 | 16q12.2 | chr16:53300954_54355291 | 2 | IRX5,LPCAT2 |
6q25 | chr6:151418856_152937016 | 2 | ESR1 | 16q23.2 | chr16:80148327_81150805 | 1 | CDYL2 |
6q25 | chr6:151418856_152937016 | 3 | SYNE1 | 18q11.2 | chr18:23832476_25075396 | 1 | KCTD1 |
6q25 | chr6:151418856_152937016 | 5 | ESR1 | 19q12 | chr19:29777729_30777729 | 1 | CCNE1 |
6q25.1 | chr6:149086328_150086328 | 1 | TAB2 | 19q13.31 | chr19:43783447_44786513 | 1 | KCNN4 |
7q22.1 | chr7:101054599_102054599 | 1 | COL26A1 | 20p12.3 | chr20:5448227_6448227 | 1 | GPCPD1 |
7q34 | chr7:139442304_140442304 | 1 | SLC37A3 | 21q21.1 | chr21:16073983_17073983 | 1 | HSPA13,NRIP1 |
8p12 | chr8:29009616_30009616 | 1 | DUSP4 | 21q21.1 | chr21:16073983_17073983 | 2 | HSPA13,NRIP1 |
8q21.11 | chr8:75730301_76917937 | 2 | CRISPLD1 | 22q13.31 | chr22:45783297_46783297 | 1 | ATXN10 |
8q23.3 | chr8:116709548_117709548 | 1 | TRPS1 | 22q13.31 | chr22:45783297_46783297 | 2 | ATXN10,WNT7B |
8q24.21 | chr8:127424659_130041931 | 2 | FAM84B,MYC | Â | Â | Â | Â |