Fig. 4

mencRNAs linked to distal CCVs at 16q12. a Regional XLOC-93918 eQTL association plot. Red dots indicate CCVs within the region. b WashU genome browser showing annotated GENCODE genes (blue) and mencRNAs (black) within the 16q12.2 risk region. The XLOC-93918 mencRNA is highlighted in red. CCVs are shown as red colored vertical lines. The ATAC-seq data is shown as a blue histogram, histone modification ChIP-seq data is shown as black histograms, and CHi-C chromatin interactions are shown as arcs from the B80T5 breast cell line. Red arcs depict chromatin looping between CCVs and the XLOC-93918 promoter region. c Zoomed in view of CHi-C interaction and XLOC-93918