Fig. 3

Relationship between pairwise \(s_{2}^{s}\) estimated by primate genomes and NGS samples using K=14 and M=12 of different numbers of reads with bias adjustment. X-axis is the pairwise \(s_{2}^{s}\) estimated by genomes and Y-axis is the pairwise \(s_{2}^{s}\) estimated based on NGS samples after bias adjustment. a–h show the relationship between \(s_{2}^{s}\) estimated by primate genomes and adjusted \(s_{2}^{s}\) based on NGS samples of only 1 M, 3M, 5 M, 7M, 9 M, 11 M, 13 M or 15 M reads, respectively. i shows pairwise adjusted \(s_{2}^{s}\) based on mixed NGS samples. NGS samples of different numbers of reads are colored accordingly. ‘Mix’ means two NGS samples have different numbers of reads (e.g., between 1 M and 5 M or between 7 M and 11 M) and is colored in gray. The root mean squared error (RMSE) and Spearman correlation coefficients (SPC) between pairwise \(s_{2}^{s}\) estimated based on NGS samples and genomes are shown on each subplot