Skip to main content
Fig. 7 | Genome Biology

Fig. 7

From: tmap: an integrative framework based on topological data analysis for population-scale microbiome stratification and association studies

Fig. 7

Systematic characterization of the multiscale pattern of environment types associated with the Earth’s microbiomes. a Ranking of EMPO, ENVO, and other metadata based on SAFE enriched score. Metadata is colored based on their categories. The relative order of EMPO classes among the ranking is highlighted by surrounded rectangles in gray. b PCA of SAFE scores of EMP metadata and taxa. The top 10 metadata identified by tmap are highlighted (markers with edge color of gray) and annotated with their names. Marker size is scaled according to SAFE enriched score. Colors of metadata are the same as that in the ranking, and taxa are in red. c Co-enrichment network of EMPO classes. Node colors are based on EMPO classes. Edge width of the network is the same as that of Fig. 5. Interconnections among the nodes in the network reflect the hierarchy of EMPO levels. Child classes of higher levels are connected to their parent classes of lower levels and are interconnected to each other. d Co-enrichment network of host metadata (host scientific name). Classification of the hosts are curated manually and colored accordingly. The co-enrichment network indicates that hosts of the same class appear to be more co-enriched when accounting for their association with the Earth’s microbiomes

Back to article page
\