Fig. 6
From: Common DNA sequence variation influences 3-dimensional conformation of the human genome
Summary of findings related to 3D chromatin variability and genetic influence. a There are thousands of regions that vary between individuals in one or more features of 3D chromatin conformation. b These regions tend to vary across individuals in multiple 3D chromatin features as well as in histone modifications, TF binding, and gene expression. c We identify hundreds of QTLs associated with 3D chromatin variation at a subset of these variable regions. d SNPs that disrupt CTCF binding motifs modulate chromatin loop strength