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Table 4 Comparison of scSplit and demuxlet performance in demultiplexing multiplexed eight individually genotyped PBMC samples (TPR true positive rate, FDR false discovery rate); total cell numbers: 6145; reads per cell: 33,119; informative SNVs: 22,757; runtime for matrices building: 45 min; runtime for cell assignment: 35 min

From: Genotype-free demultiplexing of pooled single-cell RNA-seq

scSplit vs demuxlet

TPR

FDR

Cohen’s Kappa

Singlets

0.80

0.18

0.63

Doublets

0.12

0.92