Label | Description | Type | Mapping |
---|---|---|---|
Avg num input TFs | Average number of input genes co-regulating the differentially regulated target. | Network | 1-to-1 |
Clust coef (g) | Ratio of cliques over all possible cliques in the network. Large values are indicative of small-world networks. Calculated on the undirected regulatory network. | Network | 1-to-1 |
Clust coef (l) | Average of clustering coefficients calculated per node. Calculated on the undirected network. | Network | 1-to-1 |
Density diffnet | Network density of the true differential network. Here the differential association network is used. | Network | 1-to-1 |
Density source | Network density of the source regulatory network. Density is calculated as the ratio of observed edges over the total number of possible edges (N choose 2) for N edges. | Network | 1-to-1 |
Diameter | Calculated as the longest of all shortest paths in the network and is indicative of the linear size of the network. Calculated on the undirected network. | Network | 1-to-1 |
Eigen centrality | Eigen centrality of each perturbed (knockdown) node. Calculated on the undirected network. | Network | 1-to-many |
Input means | Mean value of the distribution each input gene | Model | 1-to-many |
Input vars | Variance of the distribution of each input gene | Model | 1-to-many |
KD sample props | The smaller proportion of the population resulting from a knockdown. 0.2 if the proportions are 0.2 and 0.8. | Model | 1-to-many |
Num co-targeted | Number of differentially regulated targets | Network | 1-to-1 |
Num inputs | Number of input nodes in the source regulatory network. | Network | 1-to-1 |
Num KD genes | Number of perturbed genes (knockdown). | Model | 1-to-1 |
Num TFs | Number of regulators in the source regulatory network (both inputs and downstream). | Network | 1-to-1 |
Radius | Minimum eccentricity of any node where eccentricity of a node is the shortest distance to the farthest node. Calculated on the undirected network. | Network | 1-to-1 |
Var of input cors | Variance of the correlations between relative abundances of input genes. | Model | 1-to-1 |