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Fig. 7 | Genome Biology

Fig. 7

From: HOPS: a quantitative score reveals pervasive horizontal pleiotropy in human genetic variation is driven by extreme polygenicity of human traits and diseases

Fig. 7

Replication analysis for the genome-wide pleiotropy study. We used 372 UK Biobank heritable medical traits as our discovery dataset, and independent datasets of 73 complex traits and diseases and 430 blood metabolites as replication datasets. In each case, expected fraction of replication was empirically determined using a permutation analysis

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