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Fig. 4 | Genome Biology

Fig. 4

From: The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens

Fig. 4

Performance evaluation based on Smin for the top-performing methods in 3 ontologies. Evaluation was carried out on No knowledge benchmarks in the full mode. a–c: bar plots showing Smin of the top 10 methods. The 95% confidence interval was estimated using 10,000 bootstrap iterations on the benchmark set. Coverage of the methods was shown as text inside the bars. Coverage is defined as the percentage of proteins in the benchmark which are predicted by the methods. d–f: remaining uncertainty-missing information (RU-MI) curves for the top 10 methods. The perfect prediction should have Smin=0, at the bottom left corner of the plot. The dot on the curve indicates where the minimum semantic distance is achieved

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