Fig. 3

Example of Houseman cell type-specific CpGs measured on the 450k microarray platform, but not measured on the RRBS platform. a The cell type-specific CpG and the cell type-specific region of CpGs (or differentially methylated regions, DMR) were both identified using the purified CD8T cell, CD4T cell, Natural Killer (NK), B cell, Monocytes (Mono) and Granulocytes (Gran) cell types from [1]. b In the whole blood DNAm data from one individual (GEO Accession GSE95163) measured on two platforms (450k and RRBS), the cell type-specific CpG from Houseman et al. [3] is not measured on the RRBS platform. However, using a cell type-specific region (DMR), we are able to measure the methylation level by averaging across the region in both the 450k and RRBS platform for this sample (dotted lines)