Fig. 2

Evidence for platform-dependent bias. a Observed DNAm levels from one region in same N=10 individuals (two-platform dataset – GEO Accession GSE95163) measured on two platform technologies: Illumina 450k (red) and RRBS (blue). b Density of DNAm levels measured on the 450k platform (red) and RRBS platform (blue) in regions that are either methylated (dashed line) or not methylated (solid line). Regions were identified by searching for regions in purified whole blood cell types from Reinius et al. [1] that appeared either methylated or not methylated in all six purified cell types