Fig. 5From: Fueling ab initio folding with marine metagenomics enables structure and function predictions of new protein familiesFlowchart of multiple sequence alignment construction. (a) Generation of Pfam Tara sequences. (b) Selection of effective Pfam families. (c) Selection of representative sequence of Pfam families. (d) Construction of new HMM models. (e) Final MSA generation using the new HMM modelBack to article page