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Table 1 Computational time for analyzing differently sized data sets, for count-based mQTL mapping methods. Computing time is based on analysis of 100,000 SNP-CpG pairs with baseline simulation parameters and varying sample size, using a single thread on a Xeon E5-2683 2.00-GHz processor

From: IMAGE: high-powered detection of genetic effects on DNA methylation using integrated methylation QTL mapping and allele-specific analysis

Method Sample size Time (min)
IMAGE 50 295.87
100 410.10
150 543.48
IMAGE-I 50 81.10
100 63.93
150 108.27
IMAGE-A 50 16.63
100 36.51
150 69.25
MACAU 50 214.85
100 476.58
150 883.60
BB 50 417.63
100 2029.44
150 3967.03