Skip to main content
Fig. 4 | Genome Biology

Fig. 4

From: Maturation of the infant rhesus macaque gut microbiome and its role in the development of diarrheal disease

Fig. 4

Impact of diarrhea on the taxonomy of the rhesus gut microbiome. a Growth trajectory of asymptomatic monkeys, and those that experienced diarrhea (unpaired t-test at each time point, **p < 0.01, ***p < 0.001). b PcoA of unweighted UniFrac distances at the 1-month time point (prior to diarrhea) and at the 8-month time point (after diarrhea). c The contribution of host status to the total variance in the weighted and unweighted UniFrac dissimilarity matrices within each time point measured using PERMANOVA (Adonis with 10,000 permutations). d UniFrac distances illustrating inter-group variation at the 1-month time point (prior to diarrhea) and at the 8-month time point (after diarrhea) (one-way ANOVA p < 0.001, with Holm-Sidak’s multiple comparison test, **p < 0.01, ****p < 0.0001). e LEfSe (Log10 LDA score > 2) illustrating taxa that are significantly different between infants that remained asymptomatic and those that had diarrhea at the 8-month time point. f Violin plot of the relative abundance of Campylobacter and Helicobacter at each time point, each point represents an individual sample with solid lines indicating the median value for that age group (one-way ANOVA p < 0.001, with Holm-Sidak’s multiple comparison test, **p < 0.01, ***p < 0.001)

Back to article page