Fig. 5

Performance evaluation in allelic comparison. a,bp value density of the three evaluated methods in both cell lines. c–f logFC values between methods in each cell type shows all methods find a similar biological signal. g–i logFC values between cell types for each method. Some differences are expected, but overall values are highly correlated. j Schematic of the enrichment analysis, testing cell-line specific functional deletions for enrichment of motifs that were gained or lost by those deletions. k, l results of motif enrichment analyses. Transcription Factors with significant enrichment (FDR < 0.05) are labeled