Fig. 1
From: Analysis of Vibrio cholerae genomes identifies new type VI secretion system gene clusters
Type VI secretion system of Vibrio cholerae. a Diagrammatic depiction of the T6SS apparatus extension and contraction in V. cholerae. The apparatus is composed of a membrane-spanning and a baseplate complex, an outer contractile sheath (VipA/B), and a needle complex (Hcp and VgrG). Effectors can interact directly with VgrG or PAAR proteins, may require chaperones for delivery on the apparatus, or be carried as cargo in the T6SS apparatus. b Aux clusters 1, 2, and 4 share a canonical hcp, vgrG, tap, effector, immunity gene organization in all strains where they are found