Fig. 1
Novel KNOT interactions in transgenic plants. a Left: Hi-C interactome of Arabidopsis thaliana. The KNOT is represented by network of long-range cis- and trans-contacts found between all Arabidopsis chromosomes (see also Additional file 1: Table S1). b Hi-C interaction data representing interaction frequencies (IFs) between genomic regions on chromosome 1 (Chr1) (TIScrwn1-1, Chr1: 25151270–25156323) and Chr3 (KEE6, Chr3: 22560488–22580488). Ectopic 3D contacts can be observed between the TIS and KEE6. Left: Col-0 wild-type, Right: crwn1-1 T-DNA insertion mutant. Interaction frequencies are pooled into 50-kb genomic bins (see also Additional file 1: Figure S1A-B). c Representation of TISs on Chr1 investigated in this study. Gene and transposon density are shown to facilitate the distinction of euchromatic and heterochromatic regions