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Fig. 5 | Genome Biology

Fig. 5

From: Single-cell transcriptomics unveils gene regulatory network plasticity

Fig. 5

Changes in centralities and dynamical properties in the pancreas of type 2 diabetes (T2D). a Network from healthy and T2D subjects, in which node size is proportional to its pagerank centrality. In red are the nodes which are present in both networks and have higher pagerank in T2D (84 nodes). b Violin plots, p values, and ranking in differential expression in healthy vs. T2D tissue using all cells (1313 control cells vs 1178 T2D cells). c GO and MSigDB enrichments showing overrepresentation of diabetes-related functions in nodes with increased pagerank. d, e Several genes showing simultaneous decrease (d) or increase (e) of the five centralities have been implicated in diabetes

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