Fig. 5

ChiCMaxima performance on CHi-C data from human primary hematopoietic cells. a Numbers of interactions called by ChiCMaxima and CHiCAGO on the different datasets (three biological replicates for all, except for those denoted by an asterisk, which had four biological replicates). b Erythroblast CHi-C profile centered on the IGF1R promoter. Interactions called by ChiCMaxima are denoted as gray stripes, and those called by CHiCAGO are denoted as red points. Gene position (blue) and the erythroblast H3K27ac ChIP-seq profile (dark green) are shown below the CHi-C profile. c Bar charts showing fold enrichment over genomic background for H3K27ac peaks within the promoter-interacting sequences determined by ChiCMaxima and CHiCAGO for the nine hematopoietic cell types. d Bar charts showing fold enrichment over genomic background for H3K4me1 peaks within the promoter-interacting sequences determined by ChiCMaxima and CHiCAGO for the nine hematopoietic cell types