Fig. 7
From: DegNorm: normalization of generalized transcript degradation improves accuracy in RNA-seq analysis
DE analysis in GBM AMPK knockout data. a Box plot of estimated DI scores where condition W and T stand for control and knockout samples, respectively. b Correlation plot of DI scores shows within condition replicates had a higher correlation of degradation pattern than between condition samples. c Coefficient of variation (CV) vs. mean normalized read counts (in log scale). The bean pot under the CV plot shows the density of log of mean read counts from DegNorm. d Empirical cumulative distribution function (ECDF) of the p value from DE analysis. e Venn-diagram shows the number of claimed differentially expressed genes and pairwise overlap by DegNorm, UQ, and RUVr methods at q value threshold = 0.05