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Fig. 2 | Genome Biology

Fig. 2

From: SCRABBLE: single-cell RNA-seq imputation constrained by bulk RNA-seq data

Fig. 2

Performance evaluation using synthetic data. a A representative imputation result using simulated data containing 1000 cells and 800 genes. The data was simulated using the Splatter method [9]. The dropout rate is 83%. b t-SNE plots of the representative imputation results. c MA plots of the representative imputation results. df Imputation errors for data with different percentages of zeros in the data (71%, 83%, and 87%). The imputation error is defined as the L2 norm of the difference between the imputed data matrix and the true data matrix. Each boxplot represents the result from 100 simulated datasets. P values are based on Student’s t test

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