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Fig. 4 | Genome Biology

Fig. 4

From: Measuring the reproducibility and quality of Hi-C data

Fig. 4

Quality measures. a QuASAR-QC scores assigned to noise-injected matrices from 11 cell types (b). Total number of significant contacts above a 5% FDR threshold from noise-injected matrices from 11 cell types. c Violin plots showing the distribution of TAD boundary distances between biological replicates and noise-injected replicates for T470 cells. There is no significant change in the distribution of TAD boundary distances at any given noise level. d QuASAR-QC scores assigned to downsampled replicates from six different cell types. e Total number of significant contacts above a 5% FDR threshold from downsampled replicates from six different cell types. f Violin plots showing the distribution of distances between domain boundaries in biological replicates and noise-injected replicates for T470 cells. In panels c and f, asterisks indicate that the distribution of boundary distances is significantly larger than the null distribution, which is obtained by comparing biological replicates

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