Fig. 8

GBM patient stratification based on inosinome signature identifies two subgroups. a Unsupervised hierarchical clustering (based on Euclidean samples distance matrix) and heatmap (editing levels) calculated on the editing positions detected in at least 140 GBMs. b Kaplan-Meier curves representing the OS of GBM female patients stratified by INO-1 and INO-2. c Prognostic factors associated with the OS of de novo GBM female patients (TCGA) are analyzed with the Cox hazard regression, both univariate and multivariate analysis are shown. d Editing frequency distributions within 3′-UTR of PSMB2 in female GBM patients and Kaplan-Meier curves based on high/low editing at the PSMB2 sites in female GBM patients