Fig. 7

Inosinome signature did not overlay the previously proposed GBM subclassification. a Heatmap of clustered correlation matrix based on Spearman’s coefficients considering all the editing positions detected in proneural (PN, shown in blue), mesenchymal (M, shown in purple), neural (N, shown in orange), and classical (CL, shown in green) GBM subtypes. b Distributions of editing index (DEI) calculated at the differentially edited sites identified among GBM subtypes (see Additional file 4: Table S3). c Dendrogram plot representing Jensen-Shannon distances based on gene expression levels (cummeRbund software). ****p ≤ 0.0001, ***p ≤ 0.001, **p ≤ 0.01