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Fig. 1 | Genome Biology

Fig. 1

From: Dynamic inosinome profiles reveal novel patient stratification and gender-specific differences in glioblastoma

Fig. 1

Inosinome signature in de novo GBM compared to the normal brain and astrocytes. a Two-dimensional non-metric multi-dimensional scaling (N-MDS) ordination plots of GBM (145 samples, shown in red), cerebral cortex (132 samples, shown in blue), and normal astrocytes (12 different pools, shown in green). b Alu editing index (AEI) distributions (box plot, median). c Distributions of hyper-editing sites (box plot, median and mean values indicated as a black bar and white dots, respectively). d Non-repetitive editing index (nREI) value distributions (box plot, median). e Recoding editing index (REI) values distributions (box plot, median). Two-tailed Mann-Whitney U test was applied. ****p ≤ 0.0001

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