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Fig. 3 | Genome Biology

Fig. 3

From: clonealign: statistical integration of independent single-cell RNA and DNA sequencing data from human cancers

Fig. 3

Clone-specific gene expression in high-grade serous ovarian cancer cell lines. a Single-cell phylogeny for the OV2295R and TOV2295R HGSC cell lines inferred using a Latent Tree Model divided into four clones (TOV2295R_A, TOV2295R_B, OV2295R_C, OV2295R_D). b The scRNA-seq clone assignments for the four clone model (top), then sub-divided into eight clones (bottom). c Expression-CNA relationship on two held out chromosomes for TOV2295R validates the clonealign fit. d Top differentially expressed genes between clones in TOV2295R and e OV2295R

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