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Fig. 4 | Genome Biology

Fig. 4

From: NCBoost classifies pathogenic non-coding variants in Mendelian diseases through supervised learning on purifying selection signals in humans

Fig. 4

Comparative performance of NCBoost against state-of-the-art methods. The figure shows the area under AUROC (a) and the AUPRC (b) obtained for NCBoost (configuration of features ABCD) together with the six state-of-the-art methods (CADD, DeepSEA, Eigen, Eigen-PC, FunSeq2, and ReMM; “Methods” section) when tested on the same set of positive and negative variants described for Fig. 3

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Genome Biology

ISSN: 1474-760X

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