Fig. 1
From: Skmer: assembly-free and alignment-free sample identification using genome skims
Overview of Skmer pipeline. For both query and reference genome skims, first, the k-mer frequency profiles are used to estimate the sequencing error and coverage (top). Then, the k-mers are hashed, and a subset is retained and used to estimate the Jaccard index between the two genomes (bottom). Finally, the estimated Jaccard index and estimated sequencing coverage and error are used to compute the corrected genomic distance between the query and the reference