Table 2 Enrichment of miRNA seed match in the target sites
Seed type | Matching positions in miRNA | Downregulated targets | Non-targets | Enrichment ratio |
|---|---|---|---|---|
Seed6 | pos 2–7 | 0.86 | 0.36 | 2.40 |
Seed7a | pos 1–7 | 0.46 | 0.13 | 3.45 |
Seed7b | pos 2–8 | 0.62 | 0.15 | 4.18 |
Seed7A1 | pos 2–7 + A at target pos 1 | 0.52 | 0.13 | 4.10 |
Seed8 | pos 1–8 | 0.26 | 0.05 | 5.48 |
Seed8A1 | pos 2–8 + A at target pos1 | 0.30 | 0.04 | 6.83 |
Seed7b_not_U | Exclude miRNAs with 5′-U | 0.60 | 0.15 | 3.97 |
Seed8_not_U | Exclude miRNAs with 5′-U | 0.19 | 0.06 | 3.32 |
Seed8A1_not_U | Exclude miRNAs with 5′-U | 0.34 | 0.05 | 6.95 |