Fig. 7

Regulation of lincRNAs by transcription factors. a Clustering map illustrating the binding of transcription factors to lincRNA genes in embryos. b Clustering map illustrating the binding of transcription factors to lincRNA genes in L1 stage. c Clustering map illustrating the binding of transcription factors to lincRNA genes in L2 stage. d Clustering map illustrating the binding of transcription factors to lincRNA genes in L3. e Clustering map illustrating the binding of transcription factors to lincRNA genes in L4 stage. f Clustering map illustrating the binding of transcription factors to lincRNA genes in young adult worms. g–i Number of transcription factors regulating the 23 lincRNAs with phenotypes in this study and the other 147 lincRNAs in L1 worms (g), L2 worms (h), and L3 worms (i). j UNC-30 and UNC-55 regulated lincRNA targets. k Heatmap of the relative ChIP-seq enrichment of UNC-30 and UNC-55 lincRNA targets. All data illustrated in a-f were downloaded from modENCODE. *p < 0.05; **, p < 0.01; *** p < 0.001; p values were calculated by two-sided Mann-Whitney U test