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Fig. 2 | Genome Biology

Fig. 2

From: Systematic evaluation of C. elegans lincRNAs with CRISPR knockout mutants

Fig. 2

Phenotypic analysis of lincRNA mutants. a Summary of the phenotypic characteristics of lincRNA mutants. Six phenotypic traits (locomotion, defecation, pharyngeal pumping, egg retention, rate of development, and number of progeny) were examined in 155 lincRNA mutants. The red cell represents phenotypic data of the corresponding lincRNA mutant that were with statistically significantly different compared with the wild-type data. b Six lincRNA mutants showed uncoordination. c Six lincRNA mutants had defects in defecation. d Five lincRNA mutants showed defects in pharyngeal pumping. e Two lincRNA mutants showed egg retention defects. f Two lincRNA mutants had deceased numbers of progeny. g Four lincRNA mutants demonstrated a delay in development. n = 50. For g, data for N2 worms were reused in the figure for comparison to lincRNA mutants. For b–f, *p < 0.05; **, p < 0.01; *** p < 0.001; **** p < 0.0001; p values were calculated by the unpaired Student’s t test; for g, ***, p < 0.001, **** p < 0.0001, p values were calculated by the chi-square test

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