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Table 1 Examples of transgenesis for disease resilience and other production traits

From: Livestock 2.0 – genome editing for fitter, healthier, and more productive farmed animals

Genetic modification/transgenesis
Trait Species Transgene Reference(s)
Increased growth Pig Growth hormone (GH) and insulin-like growth factor 1 (IGF-1) [35,36,37]
Salmon GH (Chinook salmon), promoter (Ocean pout) [38]
Larger ratio of n-3 to n-6 fatty acids Pig Fat-1 (Caenorhabditis elegans) [39,40,41,42,43]
Reduction of the environmental impact through phosphorous & nitrogen release reduction Pig Phytase (Escherichia coli) [44]
Phytase (E. coli), xylanase (Aspergillus niger), β-glucanase (Bacillus lichenformis) [45]
Avian influenza resilience Chicken shRNA decoy (synthetic) [48]
Mastitis resilience Goat Lysozyme (human) [50]
Cow Lysostaphin (Staphylococcus simulans) [52]
PRRSV resilience Pig Histone deacetylase HDAC6 [67, 94]
  1. Abbreviations: GH growth hormone, PRRSV porcine reproductive and respiratory syndrome virus, sh short hairpin