Fig. 4

Association between expression of the Complement C4A gene in fetal brain and genetic risk for schizophrenia. a Effect sizes of SNPs from schizophrenia GWAS [36] plotted against their effect sizes as fetal brain cis-eQTL for C4A. The triangular data point indicates the variant with the lowest P-SMR. Error bars are the standard errors of SNP effects. b Homozygotes for the schizophrenia-associated C-allele of rs9267544 exhibit increased expression of C4A in fetal brain compared with heterozygotes for this SNP. Error bars represent standard errors