Fig. 3
CRISPRO linear maps. a z-score transformed guide RNA fitness scores for 3 cell lines for PLK1 from the dataset of Munoz et al. [7] b z-score transformed guide RNA fitness scores for three cell lines for AURKA from the dataset of Munoz et al. [7] c z-score transformed guide RNA fitness scores for 3 cell lines for CTNNB from the dataset of Munoz et al. [7]. d MAPK1/ERK2 mutant abundance following DOX induction, relative to early time point (ETP vs. DOX) and MAPK1/ERK2 mutant abundance following DOX induction in the presence of 3Ā Ī¼M VRT-11E relative to ETP (ETP vs. VRT), from the dataset of Brenan et al. [32]