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Table 3 Significantly enriched gene ontology (GO) terms based on SweeD

From: Genomes reveal marked differences in the adaptive evolution between orangutan species

GO term

GO description

P FDRa

No. of genesb

West Alas (P. abelii)

 GO:0007215

Glutamate receptor signaling pathway

0.0004

9/35

 GO:0035235

Ionotropic glutamate receptor signaling pathway

0.0045

5/11

 GO:0099565

Chemical synaptic transmission, postsynaptic

0.0066

8/44

 GO:0060079

Excitatory postsynaptic potential

0.0066

8/43

 GO:0060078

Regulation of postsynaptic membrane potential

0.0066

9/58

 GO:0061000

Negative regulation of dendritic spine development

0.0175

3/4

 GO:0120036

Plasma membrane bounded cell projection organization

0.0184

31/608

 GO:0030030

Cell projection organization

0.0227

31/617

  1. aP value after adjustment for multiple testing; bThe number of unique genes found for the given GO term related to the total number of genes that could be found at most for this term
  2. Listed GO terms were significantly enriched in the analysis of all protein-coding candidate genes of the SweeD selection tests. We only report GO terms related to biological processes