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Table 2 Significantly enriched gene ontology (GO) terms based on iHS

From: Genomes reveal marked differences in the adaptive evolution between orangutan species

GO term

GO description

P FDRa

No. of genesb

Northeast Alas (P. abelii)

 GO:0050877

Neurological system process

0.0065

31/818

 GO:1903433

Regulation of constitutive secretory pathway

0.0178

2/2

 GO:0007268

Synaptic transmission

0.0314

14/274

 GO:0007612

Learning

0.0383

8/105

 GO:0030534

Adult behavior

0.0477

9/135

 GO:0044708

Single-organism behavior

0.0492

15/320

West Alas (P. abelii)

 GO:0042254

Ribosome biogenesis

0.0173

10/110

 GO:0021987

Cerebral cortex development

0.0215

9/90

 GO:0050919

Negative chemotaxis

0.0367

5/23

 GO:0021825

Substrate-dependent cerebral cortex tangential migration

0.0500

3/5

Northeast Borneo (P. pygmaeus morio)

 GO:2000552

Negative regulation of T-helper 2 cell cytokine production

0.0500

2/2

  1. aP value after adjustment for multiple testing; bThe number of unique genes found for the given GO term related to the total number of genes that could be found at most for this term
  2. Listed GO terms were significantly enriched in the analysis of all protein-coding candidate genes of the iHS selection tests. We only report GO terms related to biological processes