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Table 1 Significantly enriched gene ontology (GO) terms based on MCM

From: Genomes reveal marked differences in the adaptive evolution between orangutan species

GO term GO description P FDRa No. of genesb
North Sumatra (P. abelii)
 GO:0005524 ATP binding 1.82 × 10−4 9/541
 GO:0006200 Obsolete ATP catabolic process 2.47 × 10−4 5/125
 GO:0007588 Excretion 2.79 × 10−4 2/41
 GO:0001822 Kidney development 5.49 × 10−4 3/83
 GO:0048403 Brain-derived neurotrophic factor binding 1.91 × 10−3 3/62
 GO:0060175 Brain-derived neurotrophic factor-activated receptor activity 1.91 × 10−3 3/62
 GO:0021987 Cerebral cortex development 3.05 × 10−3 3/62
 GO:0008331 High voltage-gated calcium channel activity 9.49 × 10−3 2/84
Northeast Borneo (P. pygmaeus morio)
 GO:0051057 Positive regulation of small GTPase-mediated signal transduction 3.13 × 10−5 2/35
 GO:0051893 Regulation of focal adhesion assembly 1.09 × 10−4 2/52
 GO:0070507 Regulation of microtubule cytoskeleton organization 1.86 × 10−4 3/69
 GO:0005540 Hyaluronic acid binding 9.56 × 10−4 2/69
 GO:0048013 Ephrin receptor signaling pathway 1.87 × 10−3 5/121
 GO:0000268 Peroxisome targeting sequence binding 2.29 × 10−3 4/87
 GO:0003025 Regulation of systemic arterial blood pressure 2.29 × 10−3 4/87
 GO:0050080 Malonyl-CoA decarboxylase activity 2.29 × 10−3 4/87
 GO:0061444 Endocardial cushion cell development 2.29 × 10−3 4/87
 GO:0070325 Lipoprotein particle receptor binding 2.29 × 10−3 4/87
 GO:0080154 Regulation of fertilization 5.72 × 10−3 4/104
  1. aP value after adjustment for multiple testing; bThe number of unique genes found for the given GO term related to the total number of genes that could be found at most for this term
  2. Listed GO terms were significantly enriched in the analysis of all protein-coding candidate genes of the MCM selection tests. We only report GO terms related to biological processes