Skip to main content

Table 1 Significantly enriched gene ontology (GO) terms based on MCM

From: Genomes reveal marked differences in the adaptive evolution between orangutan species

GO term

GO description

P FDRa

No. of genesb

North Sumatra (P. abelii)

 GO:0005524

ATP binding

1.82 × 10−4

9/541

 GO:0006200

Obsolete ATP catabolic process

2.47 × 10−4

5/125

 GO:0007588

Excretion

2.79 × 10−4

2/41

 GO:0001822

Kidney development

5.49 × 10−4

3/83

 GO:0048403

Brain-derived neurotrophic factor binding

1.91 × 10−3

3/62

 GO:0060175

Brain-derived neurotrophic factor-activated receptor activity

1.91 × 10−3

3/62

 GO:0021987

Cerebral cortex development

3.05 × 10−3

3/62

 GO:0008331

High voltage-gated calcium channel activity

9.49 × 10−3

2/84

Northeast Borneo (P. pygmaeus morio)

 GO:0051057

Positive regulation of small GTPase-mediated signal transduction

3.13 × 10−5

2/35

 GO:0051893

Regulation of focal adhesion assembly

1.09 × 10−4

2/52

 GO:0070507

Regulation of microtubule cytoskeleton organization

1.86 × 10−4

3/69

 GO:0005540

Hyaluronic acid binding

9.56 × 10−4

2/69

 GO:0048013

Ephrin receptor signaling pathway

1.87 × 10−3

5/121

 GO:0000268

Peroxisome targeting sequence binding

2.29 × 10−3

4/87

 GO:0003025

Regulation of systemic arterial blood pressure

2.29 × 10−3

4/87

 GO:0050080

Malonyl-CoA decarboxylase activity

2.29 × 10−3

4/87

 GO:0061444

Endocardial cushion cell development

2.29 × 10−3

4/87

 GO:0070325

Lipoprotein particle receptor binding

2.29 × 10−3

4/87

 GO:0080154

Regulation of fertilization

5.72 × 10−3

4/104

  1. aP value after adjustment for multiple testing; bThe number of unique genes found for the given GO term related to the total number of genes that could be found at most for this term
  2. Listed GO terms were significantly enriched in the analysis of all protein-coding candidate genes of the MCM selection tests. We only report GO terms related to biological processes